How big is the Citrulline Market | Segments & Key Players 2025

Q: What is the current size of the citrulline market?

The citrulline market was valued at USD 41.6 million in 2024 and is projected to reach USD 65.4 million by 2031.

Q: What is the growth rate of the citrulline market?

The citrulline market is expected to grow at a CAGR of 6.7% from 2025 to 2031.

Q: Which applications contribute the most in the citrulline market?

Sports nutrition, cardiovascular health supplements, fatigue management, and immune support.

Q: What is driving demand in the citrulline market?

Fitness trends, health-conscious consumers, clean-label supplements, and clinical benefits in muscle recovery.

Q: What challenges does the citrulline market face?

Limited awareness in general consumers, high purity costs, regulatory variations, and competition from other amino acids.

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Code: MTA5327

Publication Date: Jul 2025

How big is the Citrulline Market?

According to 6Wresearch internal database and industry insights, the citrulline market was valued at approximately USD 41.6 million in 2024 and is projected to reach USD 65.4 million by 2031, growing at a CAGR of 6.7%.

This growth is driven by rising demand for sports nutrition, cardiovascular health supplements, and the growing popularity of amino acid-based performance enhancers.

Key Growth Drivers of the Citrulline Market

Increased demand in supplements to increase nitric oxide and muscular endurance being used pre-workout
Raising the level of awareness about the health benefits of citrulline in keeping a healthy heart and immune system
Growth in fitness and sports nutrition business on both developed and developing markets
Study-based advantages linked to weaknesses and sport play
Increasing demand of natural and vegan sources of amino acids in health supplements

Citrulline Market Trends

The citrulline market is witnessing rising adoption in both sports’ nutrition and therapeutic applications. L-citrulline and citrulline malate are gaining popularity in bodybuilding and endurance training communities. Demand is increasing for clean-label, non-GMO, and plant-based formulations. E-commerce and direct-to-consumer brands are expanding citrulline supplement offerings. North America leads the market due to fitness trends, while Asia-Pacific shows growth potential driven by health awareness and urban wellness adoption.

Emerging Developments in the Citrulline Market

Recent developments in the citrulline market include new clinical trials highlighting its role in cardiovascular support and fatigue management. With that, manufacturers are introducing newer blends of formulations which have citrulline in combination with other amino acids such as arginine. The companies are looking towards high bioavailability variants and sustainable sourcing. Intensive collaboration of supplement companies with sports clubs is also extending the products and customer confidence.