How big is the Chromatography Resin Market | Applications & Biotech Trends 2025

Code: MTA5315 Publication Date: Jul 2025

How big is the Chromatography Resin Market?

According to 6Wresearch internal database and industry insights, the Global chromatography resin market was valued at approximately USD 2.3 billion in 2024 and is projected to reach USD 3.5 billion by 2031, growing at a CAGR of 6.2%.

This growth is fueled by rising demand for biopharmaceutical production, monoclonal antibodies, and vaccine purification processes globally.

Key Growth Drivers of the Chromatography Resin Market

  • Increasing adoption of chromatography in biologics and biosimilar drug production
  • Expansion in monoclonal antibody purification and vaccine manufacturing
  • Growing investments in life sciences and bioprocessing technologies
  • Advancements in affinity and ion exchange resins offering higher selectivity
  • Rising R&D activities and clinical trials in pharmaceutical and biotech sectors

Chromatography Resin Market Trends

The chromatography resin market is witnessing growing demand for high-performance resins with improved flow properties, binding capacities, and chemical stability. Affinity reagents especially Protein A remain the gold standard in purification of mAbs. The trend is also to have single-use and pre-packed columns to maximize efficiency in the process. Biopharma organizations are implementing continuous and automated downstream. Asia-Pacific is coming out as an important growth area as there is rising activity in biosimilar development and implemented contract manufacturing.

Emerging Developments in the Chromatography Resin Market

Recent developments in the chromatography resin market include innovations in synthetic and hybrid resins that improve recovery and scalability. Companies are investing in sustainable production of resins with longer lifespans and reduced leachable. The use of AI for resin selection and performance prediction is gaining attention. Collaborations between resin producers and bioprocessing firms are supporting the development of custom solutions for novel biologics, gene therapies, and next-generation vaccines.

Major Companies in the Chromatography Resin Market

  • Cytiva (Danaher Corporation)
  • Merck KGaA
  • Bio-Rad Laboratories, Inc.
  • Thermo Fisher Scientific Inc.
  • Tosoh Corporation
  • Purolite (an Ecolab company)
  • Repligen Corporation
  • Avantor, Inc.
  • Agilent Technologies, Inc.
  • Mitsubishi Chemical Corporation
How big is the Chromatography Resin Market : FAQ's
The chromatography resin market was valued at USD 2.3 billion in 2024 and is expected to reach USD 3.5 billion by 2031.
The chromatography resin market is projected to grow at a CAGR of 6.2% between 2025 and 2031.
Biopharmaceutical purification, monoclonal antibodies, vaccines, diagnostics, and research applications.
Biotech expansion, biosimilar production, vaccine R&D, and need for efficient downstream processing solutions.
High production cost, resin reuse limitations, supply chain constraints, and need for specialized handling.
6W monitors the market across 60+ countries Globally, publishing an annual market outlook report that analyses trends, key drivers, Size, Volume, Revenue, opportunities, and market segments. This report offers comprehensive insights, helping businesses understand market dynamics and make informed decisions.
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