How Big is the Heart Failure Market | Trends & Share 2031

Code: MTA7493 Publication Date: Aug 2025

What is the size of Heart Failure Market?

According to 6Wresearch internal database and industry insights, the Global Heart Failure Market was estimated at USD 16.5 billion in 2024 and is projected to reach USD 25.8 billion by 2031, growing at a CAGR of 8.00% during the forecast period 2025-2031.

Heart failure market is predicted to rise in the upcoming years, driven by the global increase in cardiovascular diseases, aging population, and ongoing advancements in diagnostics, therapeutics, and disease management.

Key Growth Drivers of the Heart Failure Market

  • Increasing global prevalence of heart failure and other chronic cardiovascular conditions
  • Growing aging population and sedentary lifestyles contributing to higher risk factors
  • Innovations in drug development, including SGLT2 inhibitors and ARNI therapy
  • Government support and public-private initiatives for cardiac care infrastructure
  • Improved diagnostic techniques and early detection boosting treatment demand

Heart Failure Market Trends

Heart failure market is evolving over the years with increasing adoption of combination therapies, AI-enabled risk stratification tools, and personalized treatment protocols. Another rising trend towards the integrated care models combining pharmacological and device-based treatments. Further, the patient-centric digital platforms are being leveraged to improve adherence and remote monitoring. Collectively, all these trends are reshaping the dynamics of the market.

Emerging Developments in the Heart Failure Market

Heart failure market is seeing emerging developments with gene-based therapy research, regenerative medicine approaches, and precision medicine for heart failure subtypes. On the other hand, startups have started exploring the digital therapeutics and remote cardiac rehabilitation platforms. Further, the telehealth-based heart failure clinics and predictive analytics tools are also entering the mainstream cardiac care frameworks.

List of Leading Companies in the Heart Failure Market

Below is a comprehensive list of the leading market players driving growth in this sector:

1. Novartis AG

Company NameNovartis AG
Established Year1996
HeadquartersBasel, Switzerland
Official WebsiteClick Here

Provides Entrestor, a breakthrough ARNI drug used in treating heart failure with reduced ejection fraction (HFrEF), widely adopted globally.

2. AstraZeneca

Company NameAstraZeneca
Established Year1999
HeadquartersCambridge, United Kingdom
Official WebsiteClick Here

Offers SGLT2 inhibitors used in heart failure management across multiple clinical settings.

3. Bayer AG

Company NameBayer AG
Established Year1863
HeadquartersLeverkusen, Germany
Official WebsiteClick Here

Provides innovative treatment options like vericiguat for symptomatic chronic heart failure, addressing unmet therapeutic needs.

4. Merck & Co., Inc.

Company NameMerck & Co., Inc.
Established Year1891
HeadquartersNew Jersey, United States
Official WebsiteClick Here

Actively involved in R&D of heart failure therapies, including combination drugs for cardiovascular care.

5. Amgen Inc.

Company NameAmgen Inc.
Established Year1980
HeadquartersCalifornia, United States
Official WebsiteClick Here

Focuses on heart failure treatments including biologics and investigational agents to reduce hospitalization and preserve heart function.

6. Bristol-Myers Squibb

Company NameBristol-Myers Squibb
Established Year1887
HeadquartersNew York, United States
Official WebsiteClick Here

Engaged in clinical development of cardiovascular therapies targeting heart failure progression and inflammation.

7. Cytokinetics, Inc.

Company NameCytokinetics, Inc.
Established Year1997
HeadquartersCalifornia, United States
Official WebsiteClick Here

Develops cardiac muscle activators and myotropes to improve heart function in patients with heart failure.

8. Renova Therapeutics

Company NameRenova Therapeutics
Established Year2009
HeadquartersCalifornia, United States
Official WebsiteClick Here

Specializes in gene therapy products targeting congestive heart failure and other chronic cardiac diseases.

How Big is the Heart Failure Market : FAQs

The heart failure market was estimated at USD 16.5 billion in 2024 and is projected to reach USD 25.8 billion by 2031.
Key factors include rising heart disease prevalence, growing elderly population, and innovation in therapies and diagnostics.
North America and Europe hold the largest share and Asia-Pacific is emerging rapidly with healthcare improvements.
Top companies include Novartis, AstraZeneca, Bayer, Amgen, Merck, and Cytokinetics.
6W monitors the market across 60+ countries Globally, publishing an annual market outlook report that analyses trends, key drivers, Size, Volume, Revenue, opportunities, and market segments. This report offers comprehensive insights, helping businesses understand market dynamics and make informed decisions.
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