How Big Is the Pain Relief Market | Industry, Size & Share 2031

Code: MTA7743 Publication Date: Aug 2025

How big is the Pain Relief Market?

According to 6Wresearch internal database and industry insights, the Pain Relief Market was valued at approximately USD 79.68 billion in 2024 and is projected to reach USD 140.00 billion by 2031, growing at a compound annual growth rate (CAGR) of 4.5% during the forecast period (2025-2031).

Growing demand for non-invasive pain treatments, an aging population with chronic pain needs, and the continuous development of sophisticated pharmaceuticals and pain-relieving devices are the main factors propelling the market growth.

Growth Factors for Pain Relief Market

  • An aging population that is growing and more likely to experience chronic pain
  • Growing demand for device-based, non-pharmaceutical treatments
  • Developments in analgesic formulations and delivery systems
  • Growth in over-the-counter pain relief and self-care options
  • Access to healthcare is increasing in many developing nations.
  • Growing number of operations and surgeries resulting in the need for postoperative pain management

Pain Relief Market Trends

Pain Relief Market is witnessing a growing trend toward digital and wearable pain-relief devices, offering pain management in home settings. OTC topical and transdermal products are growing in popularity as customers look for convenient, localized solutions with fewer systemic effects. To improve patient compliance, pharmacologic pain treatments are developing more targeted and longer-acting formulations. The need for pain management is rising quickly in areas with developing healthcare systems, especially Asia-Pacific. Personalized pain management plans and improved outcome tracking are made possible by the integration of analytics in connected devices. 

Emerging Developments in the Pain Relief Market

Emerging developments in the Pain Relief Market include the rise of wearable electrotherapy solutions like TENS patches and smart pain relief devices that sync with mobile apps. For long-term relief, researchers are developing injectable formulations and sustained-release analgesics. Bio-sensing materials that release medication based on feedback from the body and biodegradable patches are becoming more popular. For quicker, more efficient relief, there is a trend toward combining several mechanisms, such as cooling and analgesic. Cross-platform innovations in pain management are being fostered by collaborations between tech and pharmaceutical companies. In order to better customize treatments, personalized pain management plans that use patient data from linked devices are also becoming more popular.

List of Leading Companies in the Pain Relief Market

Below is a comprehensive list of the leading market players driving growth in this sector:

1.Pfizer Inc.

Company NamePfizer Inc.
Establishment Year1849
HeadquarterNew York, USA
Official WebsiteClick here

This company develops a broad range of pain management drugs and therapies, focusing on innovation, patient safety, and improving accessibility to quality treatments worldwide.

2.Johnson & Johnson

Company NameJohnson & Johnson
Establishment Year1886
HeadquarterNew Brunswick, USA
Official WebsiteClick here

This company offers pharmaceutical and device-based pain management solutions, leveraging research-driven innovations to improve patient outcomes and provide effective relief for chronic and acute pain worldwide.

3.GlaxoSmithKline plc (GSK)

Company NameGlaxoSmithKline plc (GSK)
Establishment Year2000
HeadquarterLondon, UK
Official WebsiteClick here

This company delivers both prescription and over-the-counter pain relief medicines, focusing on consumer wellness, innovation, and accessibility for effective pain management.

4.Sanofi S.A.

Company NameParis, France
Establishment Year2004
HeadquarterIndianapolis, USA
Official WebsiteClick here

This company offers a broad portfolio of pain relief products, from OTC brands to prescription drugs, aiming to enhance patient comfort and well-being worldwide.

5.Novartis AG

Company NameNovartis AG
Establishment Year1996
HeadquarterBasel, Switzerland
Official WebsiteClick here

This company provides pain management drugs targeting various conditions, focusing on improving quality of life through innovative, science-based, and patient-focused treatment options for worldwide healthcare needs.

6.Teva Pharmaceutical Industries Ltd.

Company NameTeva Pharmaceutical Industries Ltd.
Establishment Year1901
HeadquarterTel Aviv, Israel
Official WebsiteClick here

This company provides affordable branded and generic pain management medications, ensuring accessibility, quality, and reliability to patients worldwide through extensive distribution and strong manufacturing capabilities.

7.Bayer AG

Company NameBayer AG
Establishment Year1863
HeadquarterLeverkusen, Germany
Official WebsiteClick here

This company manufactures iconic pain relief products, combining trusted consumer healthcare brands with innovative pharmaceutical therapies to address mild to severe pain effectively.

8.Haleon plc

Company NameHaleon plc
Establishment Year2022
HeadquarterWeybridge, UK
Official WebsiteClick here

This company focuses on consumer healthcare, offering widely recognized OTC pain relief brands, with a commitment to accessibility, quality, and improving worldwide health outcomes.

9.Endo International plc

Company NameEndo International plc
Establishment Year1997
HeadquarterDublin, Ireland
Official WebsiteClick here

This company specializes in pharmaceutical pain treatments, including opioid and non-opioid drugs, delivering effective, reliable, and safe options for managing pain across diverse healthcare settings worldwide.

10.Reckitt Benckiser Group plc

Company NameReckitt Benckiser Group plc
Establishment Year1999
HeadquarterSlough, UK
Official WebsiteClick here

This company offers neuromodulation devices and targeted drug delivery systems for pain relief, combining advanced technology with patient-focused solutions to improve comfort and treatment outcomes.

How Big Is the Pain Relief Market : FAQ's

The pain relief market is projected to reach USD 140.00 billion by 2031.
The pain relief market is expected to grow at a CAGR of 4.5% during 2025-2031.
Asia-Pacific is the fastest-growing region, driven by expanding healthcare infrastructure and increasing access to pain management solutions.
Major players include Johnson & Johnson, Pfizer, Bayer, GSK, Sanofi, Reckitt Benckiser, Novartis, and Teva.
Key segments are OTC topical products, wearable pain relief devices, prescription analgesics, and sustained-release drug delivery systems.
6W monitors the market across 60+ countries Globally, publishing an annual market outlook report that analyses trends, key drivers, Size, Volume, Revenue, opportunities, and market segments. This report offers comprehensive insights, helping businesses understand market dynamics and make informed decisions.
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