Who Manufactures Cholera Vaccine | Discover Top Global Producers 2025

Who manufactures cholera vaccine?

This growth is further supported by several trends including increasing frequency of cholera outbreaks. The market is driving with the several growth factors including climate-linked flooding, conflicts, and poor sanitation. Which prompts the governments and NGOs to launch mass vaccination campaigns.

The major drivers of cholera vaccine include increasing public health campaigns in regions with recurring outbreaks, a growing traveller vaccination market, and climate-sensitive spikes in cases. The progress is continued to increase with innovation in technology for example heat-stable oral vaccines, enhanced dosing formats, and rapid diagnostics are improving reach in low-resource settings. The manufacturers like Emergent BioSolutions, Sanofi, Astellas have played their phenomenal role. Governments, NGOs, and vaccine alliances further bolster the funding and enhance cold-chain logistics which results the market growth.

List of the manufactures of cholera vaccine

1. Valneva SE

Valneva produces Dukoral, an oral cholera vaccine approved for travelers and public health use. The vaccine also provides protection against enterotoxigenic E. coli and is used in both endemic and travel markets.

2. Hilleman Laboratories

A joint venture between Merck and Wellcome Trust, Hilleman Labs is involved in developing next-generation oral cholera vaccines. The focus is on affordable and thermostable vaccines suitable for low-income regions.

3. BioFarma (PT Bio Farma)

BioFarma is Indonesia’s state-owned vaccine manufacturer and produces oral cholera vaccines for regional and global distribution. It collaborates with international agencies to expand vaccine access in Southeast Asia.

4. Incepta Vaccine Ltd.

Incepta Vaccine, part of Incepta Pharmaceuticals, is involved in vaccine R&D and manufacturing. It has collaborated with other organizations to locally produce cholera vaccines and strengthen regional capacity.

5. International Vaccine Institute (IVI)

While not a manufacturer, IVI played a key role in developing Shanchol and Euvichol, working with partners like Shantha and EuBiologics. It supports cholera vaccine technology transfer and global distribution.

6. Biological E. Limited

Biological E. is a major Indian vaccine manufacturer and has worked on oral vaccines for public health. It participates in global health initiatives and is expected to scale up production of key oral vaccines including cholera.

7. Panacea Biotec Ltd.

Panacea Biotec engages in the development of a wide range of vaccines and is involved in expanding its capabilities in enteric diseases. It has the infrastructure to potentially manufacture cholera vaccines for domestic and global needs.

8. EuBiologics Co., Ltd.

EuBiologics is the manufacturer of Euvichol and Euvichol-Plus, WHO-prequalified cholera vaccines used globally. The company plays a major role in international public health efforts through vaccine partnerships.

9. Serum Institute of India Pvt. Ltd.

Serum Institute, the world’s largest vaccine manufacturer by volume, is engaged in developing oral vaccines for public health. It is capable of producing cholera vaccines and is expanding its portfolio in this area through collaborations.

10. Shantha Biotechnics Pvt. Ltd.

Shantha Biotechnics, a Sanofi company, manufactures Shanchol, a WHO-prequalified oral cholera vaccine. It is widely used in global immunization programs, especially in low-resource and outbreak settings.

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