How big is the EGFR market?
According to 6Wresearch internal database and industry insights, the Epidermal Growth Factor Receptor (EGFR) market was valued at approximately USD 2.6 billion in 2024 and is projected to reach USD 5.9 billion by 2031, growing at a CAGR of 12.3% during the forecast period.
This growth is driven by the rising incidence of non-small cell lung cancer (NSCLC) and colorectal cancers, expanding clinical use of EGFR inhibitors, and increasing availability of targeted biologics and biosimilars. Technological advancements in precision oncology, companion diagnostics, and the emergence of next-generation EGFR inhibitors are further accelerating market expansion.
Key Growth Factors of the EGFR Market
- Rising prevalence of EGFR mutation-positive cancers, particularly NSCLC
- Increased adoption of personalized cancer therapies and precision medicine
- Development of third-generation EGFR-TKIs with improved resistance profiles
- Expanding access to molecular diagnostics and biomarker screening
- Favorable regulatory approvals and oncology R&D investments
- Growing demand for targeted therapies in emerging healthcare markets
EGFR Market Trends
The EGFR market is witnessing a shift toward mutation-specific therapies and combination regimens targeting resistance mechanisms. The integration of companion diagnostics is becoming standard in oncology treatment pathways. While North America dominates due to advanced healthcare infrastructure and drug accessibility, Asia-Pacific is seeing fast-paced growth driven by rising cancer rates and improved screening programs. The market is also seeing increased penetration of biosimilar EGFR inhibitors in cost-sensitive regions.
Emerging Developments in the EGFR Market
Research efforts are increasingly focused on next-generation EGFR inhibitors that address T790M and C797S mutations. Liquid biopsy-based EGFR detection is gaining traction for its non-invasive benefits. Pharma companies are exploring EGFR-targeting antibody-drug conjugates (ADCs) and dual-target therapies. Regulatory agencies are also streamlining approvals for mutation-specific indications, enhancing market dynamics.
Major Companies in the EGFR Market
- AstraZeneca PLC
- F. Hoffmann-La Roche Ltd.
- Pfizer Inc.
- Amgen Inc.
- Eli Lilly and Company
- Boehringer Ingelheim International GmbH
How big is the EGFR Market : FAQ's
The EGFR market was projected at approximately USD 5.9 billion by 2031.
The EGFR market is projected to grow at a CAGR of 12.3% from 2025 to 2031.
Major applications include treatment of non-small cell lung cancer, colorectal cancer, glioblastoma, and pancreatic cancer.
Challenges include drug resistance mutations, high therapy costs, and limited awareness in low-income regions.
Asia-Pacific and Latin America are expected to grow rapidly due to rising cancer incidence and improved diagnostics.
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