How Big is the Protein Drug Market | Size, Share, Growth Drivers & Forecast 2025

Code: MTA8338 Publication Date: Sep 2025

What is the size of Protein Drug Market?

According to 6Wresearch internal database and industry insights, the Protein Drug Market was estimated at USD 321 billion in 2024 and is predicted to reach USD 522 billion by 2031, expanding at a CAGR of 9.2% during the forecast period 2025-2031.

Protein Drug Market is expected to flourish in the coming years due to rising prevalence of chronic diseases, increasing use of monoclonal antibodies, growth in biotechnology innovations, and expanding demand for targeted and personalized therapies.

Key Growth Drivers of the Protein Drug Market

  • The prevalence of cancer, diabetes, and autoimmune disorders is growing
  • The adoption of monoclonal antibodies and therapeutic proteins is rising 
  • Advancements are occurring in biotechnology and recombinant DNA technologies
  • Emphasizing focus on personalized and precision medicine
  • Growing healthcare expenditure and supportive regulatory approvals

Protein Drug Market Trends

Protein Drug Market is growing with strong trends such as the rise of monoclonal antibodies and fusion proteins in cancer and autoimmune therapy. Other trends include the rapid adoption of biosimilars, expansion of protein-based vaccines, and advancements in protein engineering for improved efficacy. Further, the integration of artificial intelligence in drug discovery and increasing R&D collaborations are shaping the future landscape.

Emerging Developments in the Protein Drug Market

Protein Drug Market is developing over the years with advancements including next-generation protein therapeutics like bispecific antibodies and antibody-drug conjugates. On the other hand, expansion of biopharmaceutical manufacturing capacities globally is accelerating supply. Now, the companies are investing in novel drug delivery systems for proteins, including long-acting formulations. Moreover, the growth in partnerships between pharma companies and biotech startups is boosting innovation.

List of Leading Companies in the Protein Drug Market

Below is a comprehensive list of the leading market players driving growth in this sector:

1. Pfizer Inc.

Company NamePfizer Inc.
Established Year1849
HeadquartersNew York, United States
Official WebsiteClick Here

Pfizer develops protein-based drugs including monoclonal antibodies and vaccines, emphasizing large-scale biopharma innovation and global reach.

2. Amgen Inc.

Company NameAmgen Inc.
Established Year1980
HeadquartersCalifornia, United States
Official WebsiteClick Here

Amgen is a leader in protein therapeutics including biologics and biosimilars, with a focus on oncology, cardiovascular, and inflammatory diseases.

3. Roche Holding AG

Company NameRoche Holding AG
Established Year1896
HeadquartersBasel, Switzerland
Official WebsiteClick Here

Roche provides protein drugs such as monoclonal antibodies for cancer and autoimmune diseases, emphasizing R&D and precision medicine.

4. Novartis AG

Company NameNovartis AG
Established Year1996
HeadquartersBasel, Switzerland
Official WebsiteClick Here

Novartis offers therapeutic proteins and biosimilars across multiple therapeutic areas, with a focus on oncology, rare diseases, and global access.

5. Johnson & Johnson (Janssen Biotech)

Company NameJohnson & Johnson (Janssen Biotech)
Established Year1886
HeadquartersNew Jersey, United States
Official WebsiteClick Here

J&J develops monoclonal antibodies and protein-based therapies, emphasizing immunology, oncology, and innovative healthcare solutions.

6. Merck & Co., Inc.

Company NameMerck & Co., Inc.
Established Year1891
HeadquartersNew Jersey, United States
Official WebsiteClick Here

Merck offers therapeutic proteins and vaccines, focusing on cancer immunotherapy, infectious diseases, and bioscience innovations.

7. Eli Lilly and Company

Company NameEli Lilly and Company
Established Year1876
HeadquartersIndiana, United States
Official WebsiteClick Here

Eli Lilly produces protein drugs for diabetes, oncology, and immunology, emphasizing biologics manufacturing and global therapeutic expansion.

8. Bristol Myers Squibb

Company NameBristol Myers Squibb
Established Year1887
HeadquartersNew York, United States
Official WebsiteClick Here

BMS develops monoclonal antibodies and fusion proteins, with a major focus on oncology, cardiovascular, and autoimmune disease therapies.

How Big is the Protein Drug Market : FAQ's

The Protein Drug market was estimated at USD 321 billion in 2024 and is projected to reach USD 522 billion by 2031.
Growth factors include prevalence of chronic diseases, adoption of therapeutic proteins, biotech advancements, and regulatory support.
Oncology, diabetes, autoimmune disorders, and infectious disease treatment are key adopters.
Major companies include Pfizer, Amgen, Roche, Novartis, Johnson & Johnson, Merck, Eli Lilly, and Bristol Myers Squibb.
6W monitors the market across 60+ countries Globally, publishing an annual market outlook report that analyses trends, key drivers, Size, Volume, Revenue, opportunities, and market segments. This report offers comprehensive insights, helping businesses understand market dynamics and make informed decisions.
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