Top Pharmaceutical Companies in USA | Suppliers 2025

Code: MTA8043 Publication Date: Aug 2025

Top Pharmaceutical Companies in USA

According to 6Wresearch internal database and industry insights, the USA Pharmaceutical Market is expected to experience steady growth, registering a robust CAGR of 8.5% during the forecast period (2025–2031).

This growth is driven by rising healthcare needs, continuous innovation in drug development, and increased investments in biotechnology and personalized medicine. In addition, a strong regulatory framework, advanced R&D infrastructure, and an aging population continue to support the expansion of the pharmaceutical sector in the United States.

This report emphasizes the Top Pharmaceutical Companies in USA, as acknowledged through widespread analysis conducted by 6Wresearch internal database. Directed by in-depth market evaluation and industry experts, these leading companies have been known as the primary leaders driving growth and innovation in the USA Pharmaceutical Industry.

List of Leading Companies in the USA Pharmaceutical Market

Below is a comprehensive list of the leading market players driving growth in this sector:

1. Pfizer Inc.

Company NamePfizer Inc.
Established Year1849
HeadquartersNew York, New York, United States
Official WebsiteClick Here

Pfizer is one of the largest pharmaceutical companies globally, known for its wide-ranging drug portfolio and recent advancements in vaccines, oncology, and rare diseases.

2. Johnson & Johnson

Company NameJohnson & Johnson
Established Year1886
HeadquartersNew Brunswick, New Jersey, United States
Official WebsiteClick Here

Through its Janssen Pharmaceuticals division, Johnson & Johnson delivers innovative therapies across immunology, infectious diseases, neuroscience, and oncology.

3. Merck & Co., Inc.

Company NameMerck & Co., Inc.
Established Year1891
HeadquartersRahway, New Jersey, United States
Official WebsiteClick Here

Merck is a leading global biopharmaceutical company focused on cancer therapies, vaccines, and chronic disease treatments, backed by cutting-edge R&D.

4. AbbVie Inc.

Company NameAbbVie Inc.
Established Year2013
HeadquartersNorth Chicago, Illinois, United States
Official WebsiteClick Here

AbbVie is widely recognized for its flagship drug Humira and expanding specialty medicine portfolio across immunology, neurology, and oncology.

5. Bristol Myers Squibb

Company NameBristol Myers Squibb
Established Year1858
HeadquartersNew York, New York, United States
Official WebsiteClick Here

Bristol Myers Squibb is known for its strong presence in oncology, immunology, and cardiovascular treatment segments with a pipeline focused on innovative therapies.

6. Amgen Inc.

Company NameAmgen Inc.
Established Year1980
HeadquartersThousand Oaks, California, United States
Official WebsiteClick Here

Amgen is a pioneer in biotechnology-based drug development, focusing on therapies in oncology, nephrology, and inflammatory diseases.

7. Gilead Sciences, Inc.

Company NameGilead Sciences, Inc.
Established Year1987
HeadquartersFoster City, California, United States
Official WebsiteClick Here

Gilead is a research-driven company renowned for its leadership in antiviral drugs, including HIV and hepatitis therapies, along with recent expansions into oncology.

8. Moderna, Inc.

Company NameModerna, Inc.
Established Year2010
HeadquartersCambridge, Massachusetts, United States
Official WebsiteClick Here

Moderna is a biotech innovator leading the way in mRNA technology and vaccine development.

9. Eli Lilly and Company

Company NameEli Lilly and Company
Established Year1876
HeadquartersIndianapolis, Indiana, United States
Official WebsiteClick Here

Eli Lilly is a major player in diabetes, oncology, and neuroscience, offering a robust pipeline and market-leading biologics and small molecules.

10. Regeneron Pharmaceuticals, Inc.

Company NameRegeneron Pharmaceuticals, Inc.
Established Year1988
HeadquartersTarrytown, New York, United States
Official WebsiteClick Here

Regeneron is a fast-growing biotechnology company known for its monoclonal antibody therapies, with a strong presence in ophthalmology, immunology, and rare diseases.

Top Pharmaceutical Companies in USA : FAQs

USA Pharmaceutical Market is poised for growth, exhibiting a CAGR of 8.5% during 2025–2031.
Key drivers include technological advancements in drug development, a strong regulatory and research ecosystem, and demand for biologics and personalized treatments.
Some of the prominent players include Pfizer, Merck & Co., Johnson & Johnson, AbbVie, Bristol Myers Squibb, and Eli Lilly, among others.
6W monitors the market across 60+ countries Globally, publishing an annual market outlook report that analyses trends, key drivers, Size, Volume, Revenue, opportunities, and market segments. This report offers comprehensive insights, helping businesses understand market dynamics and make informed decisions.
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