What is the market size of High-Performance Liquid Chromatography | Key Players & Strategic Developments 2025

Code: MTA10785 Publication Date: Nov 2025

What is the size of High-Performance Liquid Chromatography Market?

According to 6Wresearch internal database and industry insights, the Global High-Performance Liquid Chromatography (HPLC) Market was estimated at USD 6.5 billion in 2024 and is projected to reach USD 10.8 billion by 2031, expanding at a CAGR of 7.6% during the forecast period 2025-2031.

There are numbers of factors which are contributing in the expansion of the market includerising demand for analytical and quality control testing in pharmaceutical and biotechnology sectors, technological advancements in HPLC instruments, increasing use in food safety and environmental testing, and growing research activities in life sciences.

Key Growth Drivers of the High-Performance Liquid Chromatography Market

  • Rising demand for advanced analytical techniques in pharmaceuticals
  • Growing applications in food and beverage testing for contaminants
  • Increasing adoption in environmental and water quality monitoring
  • Advancements in HPLC detectors, columns, and automation
  • Expanding R&D activities in biotechnology and chemical industries
  • Rising need for precise separation and identification of complex compounds

High-Performance Liquid Chromatography Market Trends

High-Performance Liquid Chromatography Market is witnessing significant growth with notable trends such as adoption of ultra-high-performance liquid chromatography (UHPLC) for faster and high-resolution analysis. Integration with mass spectrometry (HPLC-MS) is increasing across pharmaceutical and biotech labs. Increasing use of miniaturized and portable HPLC systems is gaining traction. The shift towards automated sample preparation and high-throughput screening is boosting adoption. Further, rising investments in quality control and regulatory compliance across industries are accelerating market expansion. The use of environmentally friendly and low-solvent HPLC methods is also emerging.

Emerging Developments in the High-Performance Liquid Chromatography Market

High-Performance Liquid Chromatography Market is evolving with developments in high-efficiency columns, novel stationary phases, and enhanced detection systems. Market has noticed increasing R&D in ultra-fast and microfluidic HPLC systems. Further, the collaborations between HPLC instrument manufacturers and life science research organizations are growing. Adoption of software-driven automation and AI-assisted data analysis is increasing. Development of hybrid HPLC technologies for multi-dimensional separation is underway. Expansion of analytical services in emerging sectors is contributing to market growth. The trend of eco-friendly and solvent-reducing HPLC techniques is gaining prominence.

List of Leading Companies in the High-Performance Liquid Chromatography Market

Some of the leading companies include:

  • Agilent Technologies
  • Waters Corporation
  • Shimadzu Corporation
  • Thermo Fisher Scientific
  • PerkinElmer Inc.
  • JASCO Corporation
  • Hitachi High-Tech Corporation

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